Show HN: Fly-harness – Agent = Model and harness for running biological sims

Category: ai-ml

Tags: neuroscience, simulation, neural-networks, bio-simulation, agent-framework

Score: 5.5/10 (Innovation: 6, Technical: 5, Documentation: 7, Utility: 4)

fly-harness is a Python framework that abstracts a neural simulation harness behind a swappable ModelBackend contract, allowing integration of various biological simulators (e.g., fly connectomes, C. elegans) without hard dependencies. It notably includes an OpenRouter-shaped router for bio-sim models, but the core is thin and heavily dependent on third-party models for real utility.

Target audience: computational neuroscientists, AI researchers, simulation engineers

Repository: https://github.com/acnlabs/fly-harness · Python · MIT

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